The Journal of Microbiology

, Volume 46, Issue 1, pp 29–33

Genetic variation and geographic distribution of megalocytiviruses

  • Jun-Young Song
  • Shin-Ichi Kitamura
  • Sung-Ju Jung
  • Toshiaki Miyadai
  • Shinji Tanaka
  • Yutaka Fukuda
  • Seok-Ryel Kim
  • Myung-Joo Oh
Article

DOI: 10.1007/s12275-007-0184-6

Cite this article as:
Song, JY., Kitamura, SI., Jung, SJ. et al. J Microbiol. (2008) 46: 29. doi:10.1007/s12275-007-0184-6

Abstract

Viruses belonging to the genus Megalocytivirus in the family Iridoviridae have caused mass mortalities in marine and freshwater fish in Asian countries. In this study, partial major capsid protein (MCP) gene of seven Japanese and six Korean megalocytiviruses was sequenced and compared with the known megalocytiviruses to evaluate genetic variation and geographic distribution of the viruses. Comparison of MCP gene nucleotide sequences revealed sequence identity of 92.8% or greater among these 48 isolates. A phylogenetic tree clearly revealed three clusters: genotype I including nine Japanese isolates, thirteen Korean isolates, one Chinese isolates, one Thailand isolate and one South China Sea isolate; genotype II including five freshwater fish isolates in Southeast Asian countries and Australia; and the remaining genotype III mainly consisted of flatfish isolate in Korea and China. This suggests that viruses belonging to the genotype I widely distribute among various fish species in many Asian countries. Conversely, the epidemic viruses belonged to genotype II and III are may be still locally spreading and constrained in their prevalence to the limited host fish species, i.e., genotype II viruses mainly distribute in Southeast Asian countries, whereas genotype III viruses distribute in flatfish species in Korea and China.

Keywords

megalocytivirusiridovirusgenetic variationgeographic distribution

Copyright information

© The Microbiological Society of Korea 2008

Authors and Affiliations

  • Jun-Young Song
    • 1
  • Shin-Ichi Kitamura
    • 1
  • Sung-Ju Jung
    • 2
  • Toshiaki Miyadai
    • 3
  • Shinji Tanaka
    • 4
  • Yutaka Fukuda
    • 5
  • Seok-Ryel Kim
    • 2
  • Myung-Joo Oh
    • 2
  1. 1.Center for Marine Environmental StudiesEhime UniversityMatsuyamaJapan
  2. 2.Department of Aqualife MedicineChonnam National UniversityYeosuRepublic of Korea
  3. 3.Department of Marine BioscienceFukui Prefectural UniversityObamaJapan
  4. 4.Mie Prefectural Science and Technology Promotion CenterOwase, MieJapan
  5. 5.Oita Institute of Marine and Fisheries ScienceKamiura, Minami-Amabe, OitaJapan