Research Articles Drug Actions

Archives of Pharmacal Research

, 34:1143

First online:

Determining the difference in medication compliance between the general patient population and patients receiving antihypertensive therapy: A case study

  • Josip CuligAffiliated withDepartment of Pharmacoepidemiology, Andrija Stampar Institute of Public HealthDepartment of Pharmacology, School of Medicine, Josip Juraj Strossmayer University Osijek
  • , Marcel LeppéeAffiliated withDepartment of Pharmacoepidemiology, Andrija Stampar Institute of Public Health Email author 
  • , Jelena BoskovicAffiliated withFaculty of Pharmacy and Biochemistry, University of Zagreb
  • , Mirela EricAffiliated withDepartment of Anatomy, School of Medicine, University of Novi Sad

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

This study addressed the issue of medication compliance in general, compliance with antihypertensive therapy, and the relationship between these two groups. In addition to determining the reasons for noncompliance with therapy prescription, the aim of this study was to also establish whether it was considered feasible by the patients to comply with their physician’s instructions and whether the patients believed that the prescribed therapy was beneficial to their health. Hypertensive patients were compared to the total study population according to age groups. The study was designed as a cross-sectional survey with the use of a 33-item selfadministered questionnaire. The study included 635 individuals who were collecting or buying drugs for the treatment of chronic diseases, with special reference to subjects taking antihypertensive agents (n = 361). More than half (n = 361; 56.9%) of the 635 study subjects were on therapy for arterial hypertension and possibly for some other diseases. The great majority of study subjects reported forgetfulness as the main reason for skipping drug doses. Comparison between the total study population and the subjects treated for arterial hypertension according to age groups (compliant, noncompliant and all together) yielded no statistically significant difference. We concluded that there was no difference in medication compliance between the general patient population and patients receiving antihypertensive therapy and there was no correlation between medication compliance and age.

Key words

Compliance Medications Arterial hypertension Age