, Volume 33, Issue 5, pp 647-654
Date: 29 May 2010

Antimicrobial activity of new 4,6-disubstituted pyrimidine, pyrazoline, and pyran derivatives

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Abstract

A number of new 2,6-didisubstituted pyrimidine, pyrazoline, and pyran derivatives were synthesized starting from their chalcone derivative. The synthesized compounds displayed different degrees of antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes).