Archives of Pharmacal Research

, Volume 32, Issue 4, pp 465–480

Innovative vaccine production technologies: The evolution and value of vaccine production technologies

  • KyungDong Bae
  • JunYoul Choi
  • YangSuk Jang
  • SangJeom Ahn
  • ByungKi Hur
Review

DOI: 10.1007/s12272-009-1400-1

Cite this article as:
Bae, K., Choi, J., Jang, Y. et al. Arch. Pharm. Res. (2009) 32: 465. doi:10.1007/s12272-009-1400-1

Abstract

This review paper provides an overview of innovative technologies designed to produce bacterial, viral, recombinant subunit, and polysaccharide vaccines, as well as combination vaccines. Advances in this field are illustrated by vaccines against DTP (diphtheria-tetanus-pertussis), influenza, hepatitis B (HepB) and typhoid fever. In addition, technological trends regarding antigens, adjuvants, and preservatives in vaccines are discussed. The progress achieved in vaccine production technologies is especially important for improving the protection of vulnerable populations against infectious diseases. These at-risk groups include infants, the elderly and immunocompromized individuals, as well as people living in developing countries or emerging economies.

Key words

VaccineAntigenAdjuvantCpGVirosomeTy21a

Copyright information

© The Pharmaceutical Society of Korea 2009

Authors and Affiliations

  • KyungDong Bae
    • 1
  • JunYoul Choi
    • 1
  • YangSuk Jang
    • 1
  • SangJeom Ahn
    • 1
  • ByungKi Hur
    • 2
  1. 1.Vaccine Research InstituteCrucellBerna Biotech KoreaYonginKorea
  2. 2.Department of Biotechnology and BioengineeringInha UniversityIncheonKorea