Archives of Pharmacal Research

, Volume 31, Issue 8, pp 970–972

A new chromone glycoside from Rhododendron spinuliferum

  • Gang Chen
  • Hui Zi Jin
  • Xue Feng Li
  • Qi Zhang
  • Yun Heng Shen
  • Shi Kai Yan
  • Wei Dong Zhang
Research Articles Drug Discovery

DOI: 10.1007/s12272-001-1253-y

Cite this article as:
Chen, G., Jin, H.Z., Li, X.F. et al. Arch. Pharm. Res. (2008) 31: 970. doi:10.1007/s12272-001-1253-y

Abstract

A new chromone glycoside, 3,5,7-trihydroxylchromone-3-O-α-L-arabinopyranoside (1), together with quercetin (2), (+)-catechin (3), (−)-epi-catechin (4) were isolated from the aerial parts of Rhododendron spinuliferum. The structure of 1 was elucidated on the basis of spectroscopic and 2D-NMR spectral analysis. In addition, 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.

Key words

Rhododendron spinuliferumChromone3,5,7-Trihydroxylchromone-3-O-α-L-arabinopyranosideNitric oxide (NO) production

Copyright information

© The Pharmaceutical Society of Korea 2008

Authors and Affiliations

  • Gang Chen
    • 1
    • 2
  • Hui Zi Jin
    • 1
  • Xue Feng Li
    • 3
  • Qi Zhang
    • 2
  • Yun Heng Shen
    • 4
  • Shi Kai Yan
    • 1
  • Wei Dong Zhang
    • 1
    • 4
  1. 1.School of PharmacyShanghai Jiaotong UniversityShanghaiP. R. China
  2. 2.School of Lifescience and Pharmaceutical EngineeringNanJing University of TechnologyNanjingPR China
  3. 3.JiangXi University of Traditional Chinese MedicineKey Laboratory of Modern Chinese Preparation, Ministry of EducationNanchangChina
  4. 4.School of PharmacySecond Military UniversityShanghaiP. R. China