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Sex und Penicillin-Biosynthese in Schimmelpilzen

  • Wissenschaft
  • Biotechnologie der Pilze
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BIOspektrum Aims and scope

Abstract

Penicillium chrysogenum is the only industrial producer of the β-lactam antibiotic penicillin. Like many other biotechnologically relevant fungi, it has been considered to be asexual, since no sexual propagation has been observed under laboratory conditions. The discovery of a sexual life cycle, the functional characterization of mating-type encoded transcription factors, and a comparative genomic analysis, however, will facilitate further improvement of P. chrysogenum strains used for industrial applications.

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Authors and Affiliations

  1. Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, Universitätsstraße 150, D-44780, Bochum, Deutschland

    Kordula Becker, Julia Böhm, Tim Dahlmann & Ulrich Kück

Authors
  1. Kordula Becker
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  2. Julia Böhm
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  3. Tim Dahlmann
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  4. Ulrich Kück
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Corresponding author

Correspondence to Ulrich Kück.

Additional information

Die Arbeiten der Autoren (Tim Dahlmann, Julia Böhm, Kordula Becker, Ulrich Kück, v. l. n. r.) im Labor für „Biotechnologie der Pilze“ am Lehrstuhl für Allgemeine und Molekulare Botanik an der Ruhr-Universität Bochum werden durch die Christian-Doppler Gesellschaft (Wien) und die Sandoz GmbH (Kundl) unterstützt. Hauptarbeitsgebiet ist die genetische Manipulation industriell genutzter Schimmelpilze. Dabei kommen sowohl Methoden der klassischen Mikrobiologie und Genetik als auch moderne Techniken der funktionellen Genomik zum Einsatz.

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Becker, K., Böhm, J., Dahlmann, T. et al. Sex und Penicillin-Biosynthese in Schimmelpilzen. Biospektrum 21, 270–272 (2015). https://doi.org/10.1007/s12268-015-0571-1

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  • DOI: https://doi.org/10.1007/s12268-015-0571-1

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