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, Volume 19, Issue 3, pp 290-291

First online:

Einzelne Viruspartikel mit STORM darstellen und analysieren

Super Resolution-Mikroskopie in der Virologie
  • Dennis EggertAffiliated withHeinrich-Pette-Institut, Leibniz-Institut für Experimentelle VirologieInstitut für Physikalische Chemie, Universität HamburgForschungsgruppe Elektronenmikroskopie und Mikrotechnologie, Heinrich-Pette-Institut Email author 
  • , Rudolph ReimerAffiliated withHeinrich-Pette-Institut, Leibniz-Institut für Experimentelle VirologieForschungsgruppe Elektronenmikroskopie und Mikrotechnologie, Heinrich-Pette-Institut Email author 
  • , Jörg KukuliesAffiliated withNikon GmbH

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The stochastic optical reconstruction microscopy (STORM) enables a tenfold resolution improvement over conventional fluorescence microscopy. This allows virologists for the first time to depict individual virus particles or their components without an electron microscope in their real size. Furthermore, individual viral proteins can be localized more precisely in infected cells. This leads to a better understanding of the mechanisms of viral infections.