Adipose Tissue-derived Stem Cells: The Friendly Side of a Classic Cardiovascular Foe

  • Ricardo Sanz-Ruiz
  • María Eugenia Fernández Santos
  • Marta Domínguez Muñoa
  • Ingrid Ludwig Martín
  • Radoslaw Parma
  • Pedro L. Sánchez Fernández
  • Francisco Fernández-Avilés
Article

DOI: 10.1007/s12265-007-9006-9

Cite this article as:
Sanz-Ruiz, R., Fernández Santos, M.E., Domínguez Muñoa, M. et al. J. of Cardiovasc. Trans. Res. (2008) 1: 55. doi:10.1007/s12265-007-9006-9

Abstract

Recently, the existence of a population of stem cells located in the adipose tissue has been observed. Adipose-derived stem cells are able to differentiate into multiple cell lineages including cardiac myocytes. Hence, adipose-derived cells are emerging as a new source of adult stem cells for cardiovascular repair. In this review, we discuss the basic principles of adipose-derived stem cells (types and characteristics, obtention processes, immunophenotypic characterization, and cell potency), the initial experimental studies, and the currently ongoing clinical trials.

Keywords

Stem CellsCardiovascular RepairAdipose-derived Stem CellsAdipose TissueAPOLLO TrialPRECISE Trial

Copyright information

© Springer 2007

Authors and Affiliations

  • Ricardo Sanz-Ruiz
    • 1
  • María Eugenia Fernández Santos
    • 2
  • Marta Domínguez Muñoa
    • 1
  • Ingrid Ludwig Martín
    • 1
  • Radoslaw Parma
    • 1
  • Pedro L. Sánchez Fernández
    • 1
  • Francisco Fernández-Avilés
    • 1
  1. 1.Cardiology DepartmentHospital General Universitario Gregorio MarañónMadridSpain
  2. 2.Cell Processing UnitHospital General Universitario Gregorio MarañónMadridSpain