, Volume 26, Issue 1, pp 1-7
Date: 18 Feb 2011

Advances of bioinformatics tools applied in virus epitopes prediction

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Abstract

In recent years, the in silico epitopes prediction tools have facilitated the progress of vaccines development significantly and many have been applied to predict epitopes in viruses successfully. Herein, a general overview of different tools currently available, including T cell and B cell epitopes prediction tools, is presented. And the principles of different prediction algorithms are reviewed briefly. Finally, several examples are present to illustrate the application of the prediction tools.

Fundation items: The National Natural Science Foundations of China (30870131) and the National Key Projects in the Infectious Fields (2008ZX10002-011, 2008ZX10004-004).