Accurate 3D reconstruction of subject-specific knee finite element model to simulate the articular cartilage defects

  • Yue-fu Dong (董跃福)
  • Guang-hong Hu (胡广洪)
  • Luo-lian Zhang (张罗莲)
  • Yang Hu (胡 杨)
  • Ying-hai Dong (董英海)
  • Qing-rong Xu (徐卿荣)
Article

DOI: 10.1007/s12204-011-1199-z

Cite this article as:
Dong, Y., Hu, G., Zhang, L. et al. J. Shanghai Jiaotong Univ. (Sci.) (2011) 16: 620. doi:10.1007/s12204-011-1199-z

Abstract

The biomechanical relationship between the articular cartilage defect and knee osteoarthritis (OA) has not been clearly defined. This study presents a 3D knee finite element model (FEM) to determine the effect of cartilage defects on the stress distribution around the defect rim. The complete knee FEM, which includes bones, articular cartilages, menisci and ligaments, is developed from computed tomography and magnetic resonance images. This FEM then is validated and used to simulate femoral cartilage defects. Based on the obtained results, it is confirmed that the 3D knee FEM is reconstructed with high-fidelity level and can faithfully predict the knee contact behavior. Cartilage defects drastically affect the stress distribution on articular cartilages. When the defect size was smaller than 1.00 cm2, the stress elevation and redistribution were found undistinguishable. However, significant stress elevation and redistribution were detected due to the large defect sizes (⩾1.00 cm2). This alteration of stress distribution has important implications relating to the progression of cartilage defect to OA in the human knee joint.

Key words

3D reconstruction knee joint finite element model (FEM) cartilage defect osteoarthritis (OA) 

CLC number

R 684 

Copyright information

© Shanghai Jiaotong University and Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Yue-fu Dong (董跃福)
    • 1
  • Guang-hong Hu (胡广洪)
    • 2
  • Luo-lian Zhang (张罗莲)
    • 2
  • Yang Hu (胡 杨)
    • 2
  • Ying-hai Dong (董英海)
    • 1
  • Qing-rong Xu (徐卿荣)
    • 1
  1. 1.Department of Orthopaedics, Renji HospitalShanghai Jiaotong University School of MedicineShanghaiChina
  2. 2.Department of Plasticity EngineeringShanghai Jiaotong UniversityShanghaiChina