Environmental Health and Preventive Medicine

, Volume 16, Issue 1, pp 6–15

Polychlorinated dioxins, furans, and biphenyls in blood of children and adults living in a dioxin-contaminated area in Tokyo

  • Chiharu Tohyama
  • Iwao Uchiyama
  • Shuji Hoshi
  • Masaki Hijiya
  • Hideaki Miyata
  • Masaki Nagai
  • Satoshi Nakai
  • Mariko Yauchi
  • Satsuki Ohkubo
Regular Article

DOI: 10.1007/s12199-010-0156-z

Cite this article as:
Tohyama, C., Uchiyama, I., Hoshi, S. et al. Environ Health Prev Med (2011) 16: 6. doi:10.1007/s12199-010-0156-z

Abstract

The soil of a residential area in Tokyo was found to contain dioxins, namely polychlorinated dioxins, furans, and dioxin-like biphenyls, the levels of which exceeded the environmental guideline [1,000 pg toxic equivalent (TEQ)/g] by up to 6.8 times. To assess the exposure levels of people living in this area and to study the possible relationship of blood dioxin concentrations of children with breast milk and/or formula feeding, a health survey was carried out in 2006, involving a total of 138 people, including 66 children aged 3–15 years, and blood dioxin concentrations and the characteristics and lifestyles of these people were analyzed. Mean ± standard error of the mean (SEM) of blood dioxin concentrations (pg/g-lipid) of group 1 (3–6 years old), group 2 (7–15 years old), and group 3 (≥16 years old) were 13 ± 1.9, 6.6 ± 0.65, and 10 ± 0.54, respectively. The congener/isomer profile of dioxins in blood samples differed markedly from that of the contaminated soil samples. According to the feeding mode of children, blood dioxin concentrations (pg/g-lipid) were 17 ± 2.9 for breast milk only, 7.4 ± 0.82 for both breast milk and formula, and 4.7 ± 1.1 for formula only, with a significant difference from one another. We conclude that people living in the dioxin-contaminated area are less likely to be exposed to excessive amounts of dioxins, and that blood dioxin concentrations of children aged 3–15 years seem to be strongly affected by breast feeding duration.

Keywords

BloodBreast feedingChildrenDioxinSoil

Supplementary material

12199_2010_156_MOESM1_ESM.doc (81 kb)
Supplementary material 1 (DOC 81 kb)

Copyright information

© The Japanese Society for Hygiene 2010

Authors and Affiliations

  • Chiharu Tohyama
    • 1
  • Iwao Uchiyama
    • 2
  • Shuji Hoshi
    • 3
  • Masaki Hijiya
    • 3
  • Hideaki Miyata
    • 4
  • Masaki Nagai
    • 5
  • Satoshi Nakai
    • 6
  • Mariko Yauchi
    • 7
  • Satsuki Ohkubo
    • 7
  1. 1.Laboratory of Environmental Health Sciences, Center for Disease Biology and Integrated Medicine, Graduate School of MedicineThe University of TokyoTokyoJapan
  2. 2.Graduate School of EngineeringKyoto UniversityKyotoJapan
  3. 3.IDEA Consultants, Inc.TokyoJapan
  4. 4.Faculty of Pharmaceutical SciencesSetsunan UniversityOsakaJapan
  5. 5.Department of Public Health, Faculty of MedicineSaitama Medical UniversitySaitamaJapan
  6. 6.Graduate School of Environment and Information SciencesYokohama National UniversityKanagawaJapan
  7. 7.Public Health Center of Kita-CityTokyoJapan