Environmental Health and Preventive Medicine

, Volume 14, Issue 5, pp 267–275

Evaluation of subjective symptoms of Japanese patients with multiple chemical sensitivity using QEESI©

  • Sachiko Hojo
  • Kou Sakabe
  • Satoshi Ishikawa
  • Mikio Miyata
  • Hiroaki Kumano
Regular Article

DOI: 10.1007/s12199-009-0095-8

Cite this article as:
Hojo, S., Sakabe, K., Ishikawa, S. et al. Environ Health Prev Med (2009) 14: 267. doi:10.1007/s12199-009-0095-8

Abstract

Objectives

The Quick Environment Exposure Sensitivity Inventory (QEESI©) has been used as a questionnaire to evaluate subjective symptoms of patients with multiple chemical sensitivity (MCS), also known as idiopathic environmental intolerance, in Japan. However, no cutoff value for Japanese subjects has yet been established. We designed this study to establish a cutoff value for Japanese subjects using QEESI© for screening of MCS patients.

Methods

A questionnaire using the QEESI© was administered to 103 MCS patients and 309 healthy control subjects matched for age and sex. QEESI© scores of the two groups were compared using logistic regression analysis, receiver operating characteristic analysis, and the Mann–Whitney test.

Results

Cutoff values for Japanese subjects were determined for the Chemical Intolerance subscale (40), Symptom Severity subscale (20), and Life Impact subscale (10). The subjects whose scores exceeded the cutoff values in any two subscales accounted for 88.4% of the patients but only 14.5% of the controls.

Conclusions

Our results suggest that subjects meeting two out of three subscale criteria can be screened as “patients suffering from a low level of environmental chemicals such as MCS” in Japan.

Keywords

Multiple chemical sensitivity (MCS)Idiopathic environmental intolerance (IEI)Quick Environment Exposure Sensitivity Inventory (QEESI©)Logistic regression analysisReceiver operating characteristics (ROC) analysis

Copyright information

© The Japanese Society for Hygiene 2009

Authors and Affiliations

  • Sachiko Hojo
    • 1
  • Kou Sakabe
    • 2
    • 3
  • Satoshi Ishikawa
    • 3
  • Mikio Miyata
    • 3
  • Hiroaki Kumano
    • 4
  1. 1.Department of Environmental ScienceShokei Gakuin UniversityNatoriJapan
  2. 2.Department of Human Structure and FunctionTokai University School of MedicineKanagawaJapan
  3. 3.Division of Environmental Medical CenterKitasato Institute HospitalTokyoJapan
  4. 4.Faculty of Human SciencesWaseda UniversitySaitamaJapan