Radiological Physics and Technology

, Volume 2, Issue 1, pp 46–53

X-ray fluorescence camera for imaging of iodine media in vivo

Authors

    • The 3rd Department of SurgeryToho University School of Medicine
  • Manabu Watanabe
    • The 3rd Department of SurgeryToho University School of Medicine
  • Eiichi Sato
    • Department of PhysicsIwate Medical University
  • Akihiro Osawa
    • The 3rd Department of SurgeryToho University School of Medicine
  • Toshiyuki Enomoto
    • The 3rd Department of SurgeryToho University School of Medicine
  • Jiro Nagao
    • The 3rd Department of SurgeryToho University School of Medicine
  • Purkhet Abderyim
    • Department of Computer and Information Sciences, Faculty of EngineeringIwate University
  • Katsuo Aizawa
    • Tokyo Medical University
  • Etsuro Tanaka
    • Department of Nutritional Science, Faculty of Applied Bio-ScienceTokyo University of Agriculture
  • Hidezo Mori
    • Department of Cardiac PhysiologyNational Cardiovascular Center Research Institute
  • Toshiaki Kawai
    • Electron Tube Division #2, Hamamatsu Photonics K.K.
  • Shigeru Ehara
    • Department of Radiology, School of MedicineIwate Medical University
  • Shigehiro Sato
    • Department of Microbiology, School of MedicineIwate Medical University
  • Akira Ogawa
    • Department of Neurosurgery, School of MedicineIwate Medical University
  • Jun Onagawa
    • Department of Electronics, Faculty of EngineeringTohoku Gakuin University
Article

DOI: 10.1007/s12194-008-0042-1

Cite this article as:
Matsukiyo, H., Watanabe, M., Sato, E. et al. Radiol Phys Technol (2009) 2: 46. doi:10.1007/s12194-008-0042-1

Abstract

X-ray fluorescence (XRF) analysis is useful for measuring density distributions of contrast media in vivo. An XRF camera was developed for carrying out mapping for iodine-based contrast media used in medical angiography. Objects are exposed by an X-ray beam from a cerium target. Cerium K-series X-rays are absorbed effectively by iodine media in objects, and iodine fluorescence is produced from the objects. Next, iodine Kα fluorescence is selected out by use of a 58-µm-thick stannum filter and is detected by a cadmium telluride (CdTe) detector. The Kα rays are discriminated out by a multichannel analyzer, and the number of photons is counted by a counter card. The objects are moved and scanned by an x–y stage in conjunction with a two-stage controller, and X-ray images obtained by iodine mapping are shown on a personal computer monitor. The scan pitch of the x and y axes was 2.5 mm, and the photon counting time per mapping point was 2.0 s. We carried out iodine mapping of non-living animals (phantoms), and iodine Kα fluorescence was produced from weakly remaining iodine elements in a rabbit skin cancer.

Keywords

X-ray photon counting Energy discrimination X-ray camera X-ray fluorescence CdTe detector DDS

Copyright information

© Japanese Society of Radiological Technology and Japan Society of Medical Physics 2008