Radiological Physics and Technology

, Volume 2, Issue 1, pp 46–53

X-ray fluorescence camera for imaging of iodine media in vivo

  • Hiroshi Matsukiyo
  • Manabu Watanabe
  • Eiichi Sato
  • Akihiro Osawa
  • Toshiyuki Enomoto
  • Jiro Nagao
  • Purkhet Abderyim
  • Katsuo Aizawa
  • Etsuro Tanaka
  • Hidezo Mori
  • Toshiaki Kawai
  • Shigeru Ehara
  • Shigehiro Sato
  • Akira Ogawa
  • Jun Onagawa
Article

DOI: 10.1007/s12194-008-0042-1

Cite this article as:
Matsukiyo, H., Watanabe, M., Sato, E. et al. Radiol Phys Technol (2009) 2: 46. doi:10.1007/s12194-008-0042-1

Abstract

X-ray fluorescence (XRF) analysis is useful for measuring density distributions of contrast media in vivo. An XRF camera was developed for carrying out mapping for iodine-based contrast media used in medical angiography. Objects are exposed by an X-ray beam from a cerium target. Cerium K-series X-rays are absorbed effectively by iodine media in objects, and iodine fluorescence is produced from the objects. Next, iodine Kα fluorescence is selected out by use of a 58-µm-thick stannum filter and is detected by a cadmium telluride (CdTe) detector. The Kα rays are discriminated out by a multichannel analyzer, and the number of photons is counted by a counter card. The objects are moved and scanned by an x–y stage in conjunction with a two-stage controller, and X-ray images obtained by iodine mapping are shown on a personal computer monitor. The scan pitch of the x and y axes was 2.5 mm, and the photon counting time per mapping point was 2.0 s. We carried out iodine mapping of non-living animals (phantoms), and iodine Kα fluorescence was produced from weakly remaining iodine elements in a rabbit skin cancer.

Keywords

X-ray photon countingEnergy discriminationX-ray cameraX-ray fluorescenceCdTe detectorDDS

Copyright information

© Japanese Society of Radiological Technology and Japan Society of Medical Physics 2008

Authors and Affiliations

  • Hiroshi Matsukiyo
    • 1
  • Manabu Watanabe
    • 1
  • Eiichi Sato
    • 2
  • Akihiro Osawa
    • 1
  • Toshiyuki Enomoto
    • 1
  • Jiro Nagao
    • 1
  • Purkhet Abderyim
    • 3
  • Katsuo Aizawa
    • 4
  • Etsuro Tanaka
    • 5
  • Hidezo Mori
    • 6
  • Toshiaki Kawai
    • 7
  • Shigeru Ehara
    • 8
  • Shigehiro Sato
    • 9
  • Akira Ogawa
    • 10
  • Jun Onagawa
    • 11
  1. 1.The 3rd Department of SurgeryToho University School of MedicineMeguro-kuJapan
  2. 2.Department of PhysicsIwate Medical UniversityYahabaJapan
  3. 3.Department of Computer and Information Sciences, Faculty of EngineeringIwate UniversityMoriokaJapan
  4. 4.Tokyo Medical UniversityShinjyuku-kuJapan
  5. 5.Department of Nutritional Science, Faculty of Applied Bio-ScienceTokyo University of AgricultureSetagaya-kuJapan
  6. 6.Department of Cardiac PhysiologyNational Cardiovascular Center Research InstituteSuitaJapan
  7. 7.Electron Tube Division #2, Hamamatsu Photonics K.K.IwataJapan
  8. 8.Department of Radiology, School of MedicineIwate Medical UniversityMoriokaJapan
  9. 9.Department of Microbiology, School of MedicineIwate Medical UniversityMoriokaJapan
  10. 10.Department of Neurosurgery, School of MedicineIwate Medical UniversityMoriokaJapan
  11. 11.Department of Electronics, Faculty of EngineeringTohoku Gakuin UniversityTagajoJapan