Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis
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A voxel-based specific regional analysis system for Alzheimer’s disease (VSRAD) was used for quantitative analysis of parahippocampal atropy with 1.5-tesla (T) MRI in a voxel-wise manner. The analysis of images acquired under a different imaging condition provides an error factor that has a calculated value. Clinical application of 3T-MRI is necessary for establishing a normal data base (N-DB) specific for 3T-MRI data, which permits appropriate application of VSRAD. We established an N-DB specific for 3T-MRI for use in VSRAD. The “Z-score of the parahippocampal gyrus” was 0.79 ± 0.32, and the N-DB of each age group did not have a big deflection when we analyzed a group of physically unimpaired persons in an N-DB specific for 3T-MRI. Therefore, we were able to confirm the validity of the customized N-DB. The “Z-score of the parahippocampal gyrus” was 1.62 ± 0.47 for the N-DB of VSRAD. The numerical value was high for the group of physically unimpaired persons.
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- Customization of normal data base specific for 3-tesla MRI is mandatory in VSRAD analysis
Radiological Physics and Technology
Volume 1, Issue 2 , pp 196-200
- Cover Date
- Print ISSN
- Online ISSN
- Springer Japan
- Additional Links
- Central nervous system
- Magnetic resonance imaging (MRI)
- Voxel-based morphometry (VBM)
- Alzheimer’s disease
- Voxel-based specific regional analysis system for Alzheimer’s disease (VSRAD)
- Author Affiliations
- 1. Department of Radiological Technology, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan
- 2. Department of Radiology, University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan