Pulmonary embolism in a patient with multiple myeloma receiving thalidomide–dexamethasone therapy
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- Jeng, WJ., Kuo, MC., Shih, LY. et al. Int J Hematol (2008) 87: 542. doi:10.1007/s12185-008-0071-x
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Massive pulmonary embolism is an uncommon complication of multiple myeloma treated with thalidomide–dexamethasone regimen. In 2006, multiple myeloma was diagnosed in a 72-year-old man, who received thalidomide–dexamethasone therapy. In January 2007, echocardiography and computerized tomography identified massive pulmonary embolism in the pulmonary arteries and a deep vein thrombus of the right leg. The patient also had an elevated concentration of B-type natriuretic peptide. After heparinization and warfarin therapy, the patient’s condition improved. This is the first report of a patient with a rare complication of pulmonary embolism from thalidomide-treated multiple myeloma.