Date: 06 Dec 2013

Biopsychosocial Determinants of Health and Quality of life Among Young Women with Coronary Heart Disease

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Abstract

Scientific advances have led to substantial reductions in coronary heart disease (CHD) mortality over the past two decades. Impressive achievements in understanding sex differences in CHD outcomes are currently overshadowed by the limited exploration of the health disparities among young women with acute coronary syndromes (ACS). Even though patient-reported outcomes (PROs) such as perceived health and quality of life (QoL) independently predict cardiovascular events and mortality, there is a paucity of research on the determinants of PROs of young women. This review highlights the scientific evidence of the biological and psychosocial factors contributing to poor health and QoL among young women with ACS. Ascertaining the biopsychosocial determinants of PROs among young women will permit translation of this science into novel strategies for improved risk stratification and appropriate triage to age-specific and gender-sensitive personalized interventions that enhance self-management and reduce health differentials among this vulnerable cohort.

This article is part of the Topical Collection on Women + Heart Disease