Current Cardiovascular Risk Reports

, Volume 6, Issue 6, pp 591–600

Cardiovascular Risk in Children and Adolescents with Type 1 and Type 2 Diabetes Mellitus

Pediatrics (SS Gidding, Section Editor)

DOI: 10.1007/s12170-012-0274-9

Cite this article as:
Magge, S.N. Curr Cardiovasc Risk Rep (2012) 6: 591. doi:10.1007/s12170-012-0274-9


Rising rates of both type 1 and type 2 diabetes mellitus in children have led to increased concern regarding cardiovascular disease (CVD) risk during childhood. Diabetic children face prolonged exposure to hyperglycemia, and have increased risk of both microvascular and macrovascular disease. These circumstances may result in a generation of young adults presenting with cardiovascular outcomes, a tremendous personal and public health toll. In this article, we review CVD risk in type 1 and type 2 diabetes, discuss aspects of pathophysiology, and review current methods of CVD risk assessment. We also identify crucial areas in need of future research in order to devise effective prevention and treatment of CVD risk in children.


Type 1 diabetes mellitusType 2 diabetes mellitusLipoprotein subclass particle analysisAdipokinesAdiponectinInflammationCardiovascular riskBody mass indexPediatricsLipidsObesityCarotid intimal medial thicknessFlow mediated dilation of the brachial arteryPulse wave velocityPulse wave analysisEchocardiographyLeft ventricular massCoronary artery calcification

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Endocrinology and DiabetesThe Children’s Hospital of PhiladelphiaPhiladelphiaUSA
  2. 2.Perelman School of Medicine at the University of PennsylvaniaPhiladelphiaUSA