Annals of Behavioral Medicine

, Volume 49, Issue 1, pp 58–65

Angina Symptom Burden Associated with Depression Status Among Veterans with Ischemic Heart Disease

  • Ranak Trivedi
  • Martha Gerrity
  • John S. Rumsfeld
  • John A. Spertus
  • Haili Sun
  • Mary McDonell
  • Melanie Doak
  • Linda Lucas
  • Stephan D. Fihn
Original Article

DOI: 10.1007/s12160-014-9629-4

Cite this article as:
Trivedi, R., Gerrity, M., Rumsfeld, J.S. et al. ann. behav. med. (2015) 49: 58. doi:10.1007/s12160-014-9629-4

Abstract

Background

Angina and depression are common in ischemic heart disease (IHD), but their association remains understudied.

Purpose

This study was conducted in order to evaluate the association of 1 year change in depression with change in patient-reported outcomes of stable angina.

Methods

Five hundred sixty-nine stable angina patients completed the Seattle Angina Questionnaire and Patient Health Questionnaire (PHQ) at baseline and 1 year. Participants were divided into four groups: not depressed, new onset of depression at 1 year, remitted at 1 year, and persistently depressed. Associations between depression and angina symptoms were evaluated using regression models.

Results

Compared to those not depressed, newly depressed participants reported more angina (β = −11.7, p < 0.001) and physical limitations (β = −11.8, p < 0.001) and lower treatment satisfaction (β = −15.03, p < 0.001) and quality of life (β = −15.4, p < 0.001). Persistently depressed participants reported physical limitations (β = −7.4, p < 0.05), lower treatment satisfaction (β = −10.1, p < 0.001), and poorer quality of life (β = −10.03, p < 0.001).

Conclusions

Changes in depression scores and angina outcomes were significantly associated.

Keywords

Angina Depression Quality of life Patient-reported outcomes 

Copyright information

© The Society of Behavioral Medicine 2014

Authors and Affiliations

  • Ranak Trivedi
    • 1
    • 7
  • Martha Gerrity
    • 2
    • 3
  • John S. Rumsfeld
    • 4
  • John A. Spertus
    • 5
  • Haili Sun
    • 1
  • Mary McDonell
    • 1
  • Melanie Doak
    • 2
    • 3
  • Linda Lucas
    • 2
    • 3
  • Stephan D. Fihn
    • 6
  1. 1.VA Puget Sound Health Care SystemSeattleUSA
  2. 2.Portland VA Medical CenterPortlandUSA
  3. 3.Department of MedicineOregon Health & Science UniversityPortlandUSA
  4. 4.VA Eastern Colorado Health Care SystemDenverUSA
  5. 5.Department of MedicineUniversity of Missouri-Kansas CityKansas CityUSA
  6. 6.Office of Analytics and Business Intelligence, Department of Veterans’ Affairs, Department of MedicineUniversity of WashingtonSeattleUSA
  7. 7.Center for Innovation to Implementation, VA Palo Alto Health Care System, Department of Psychiatry and Behavioral SciencesStanford UniversityMenlo ParkUSA