Annals of Behavioral Medicine

, Volume 41, Issue 2, pp 227–234

The Effect of Telephone-Administered Cognitive–Behavioral Therapy on Quality of Life among Patients with Multiple Sclerosis

Authors

  • David Cosio
    • Edward Hines Jr. VA Hospital, Center for the Management of Complex Chronic Care
  • Ling Jin
    • Department of Preventive MedicineNorthwestern University Feinberg School of Medicine
  • Juned Siddique
    • Department of Preventive MedicineNorthwestern University Feinberg School of Medicine
    • Edward Hines Jr. VA Hospital, Center for the Management of Complex Chronic Care
    • Department of Preventive MedicineNorthwestern University Feinberg School of Medicine
Original Article

DOI: 10.1007/s12160-010-9236-y

Cite this article as:
Cosio, D., Jin, L., Siddique, J. et al. ann. behav. med. (2011) 41: 227. doi:10.1007/s12160-010-9236-y

Abstract

Background

Past research has found that a variety of physical, psychological, and social factors can affect quality of life (QOL). These previous findings suggest that interventions that address these factors could potentially improve QOL.

Purpose

The purpose of this study was to examine whether cognitive behavioral therapy (CBT) can improve QOL, and if so, explore which factors might mediate this effect.

Methods

This is a secondary analysis of a randomized controlled trial. One hundred twenty-seven participants with multiple sclerosis and depression were randomly assigned to either a telephone-administered CBT (T-CBT) or telephone-administered supportive emotion-focused therapy (T-SEFT) intervention.

Results

Patients assigned to T-CBT showed significantly greater improvements in QOL compared with those assigned to T-SEFT. The greater improvement in QOL among T-CBT recipients was mediated by improvements in depression and positive affect. There was also inconsistent support for the superior effect of CBT on QOL being mediated by improvement in fatigue.

Conclusions

T-CBT provided greater QOL benefits compared with T-SEFT, which controlled for non-specific treatment components. This study further suggests that T-CBT procedures specific to the management of depression and positive affect were uniquely useful in improving QOL.

Keywords

Multiple sclerosisMajor depressionTelemental healthCognitive behavioral therapyPositive affectMediation

Copyright information

© The Society of Behavioral Medicine 2010