Annals of Behavioral Medicine

, Volume 41, Issue 1, pp 119–130

A Randomized Controlled Trial of Behavioral Weight Loss Treatment Versus Combined Weight Loss/Depression Treatment Among Women with Comorbid Obesity and Depression

  • Jennifer A. Linde
  • Gregory E. Simon
  • Evette J. Ludman
  • Laura E. Ichikawa
  • Belinda H. Operskalski
  • David Arterburn
  • Paul Rohde
  • Emily A. Finch
  • Robert W. Jeffery
Original Article

DOI: 10.1007/s12160-010-9232-2

Cite this article as:
Linde, J.A., Simon, G.E., Ludman, E.J. et al. ann. behav. med. (2011) 41: 119. doi:10.1007/s12160-010-9232-2

Abstract

Background

Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials.

Purpose

This study examined treatment outcomes among women with comorbid obesity and depression.

Methods

Two hundred three (203) women were randomized to behavioral weight loss (n = 102) or behavioral weight loss combined with cognitive-behavioral depression management (n = 101).

Results

Average participant age was 52 years; mean baseline body mass index was 39 kg/m2. Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses (p = 0.26 and 0.55 for weight, p = 0.70 and 0.25 for depressive symptoms).

Conclusions

Depressed obese women lost weight and demonstrated improved mood in both treatment programs. Future weight loss trials are encouraged to enroll depressed women.

Keywords

ObesityDepressionComorbidityInterventionWomen

Copyright information

© The Society of Behavioral Medicine 2010

Authors and Affiliations

  • Jennifer A. Linde
    • 1
  • Gregory E. Simon
    • 2
  • Evette J. Ludman
    • 2
  • Laura E. Ichikawa
    • 2
  • Belinda H. Operskalski
    • 2
  • David Arterburn
    • 2
  • Paul Rohde
    • 3
  • Emily A. Finch
    • 4
  • Robert W. Jeffery
    • 1
  1. 1.Division of Epidemiology and Community Health, School of Public HealthUniversity of MinnesotaMinneapolisUSA
  2. 2.Group Health Research InstituteGroup Health CooperativeSeattleUSA
  3. 3.Oregon Research InstituteEugeneUSA
  4. 4.Indiana University School of MedicineIndianapolisUSA