Original Article

Annals of Behavioral Medicine

, 37:207

First online:

A Randomized Trial of Generic Versus Tailored Interventions to Increase Colorectal Cancer Screening Among Intermediate Risk Siblings

  • Sharon L. ManneAffiliated withFox Chase Cancer Center Email author 
  • , Elliot J. CoupsAffiliated withFox Chase Cancer Center
  • , Arnold MarkowitzAffiliated withMemorial Sloan-Kettering Cancer Center
  • , Neal J. MeropolAffiliated withFox Chase Cancer Center
  • , Daniel HallerAffiliated withThe Hospital of the University of Pennsylvania
  • , Paul B. JacobsenAffiliated withMoffitt Cancer Center
  • , Lina JandorfAffiliated withMount Sinai School of Medicine
  • , Susan K. PetersonAffiliated withThe University of Texas M.D. Anderson Cancer Center
  • , Samuel LeskoAffiliated withNortheast Regional Cancer Institute
    • , Steven PilipshenAffiliated withColorectal Surgical Associates of New Jersey
    • , Gary WinkelAffiliated withCity University of New York

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Individuals with a sibling who has had colorectal cancer diagnosed before age 61 are at increased risk for colorectal cancer and may derive particular benefit from screening. Tailored interventions may increase participation in appropriate colorectal cancer screening.


This study evaluated the efficacy of two tailored interventions and a generic print intervention.


Participant siblings (N = 412) who were not up-to-date with colorectal cancer screening were randomly assigned to receive either a generic print pamphlet, a tailored print pamphlet, or a tailored print pamphlet and tailored counseling call. Colorectal cancer screening 6 months after the baseline interview was the outcome measure.


Results indicated that colorectal cancer screening adherence increased among intermediate risk siblings enrolled in all three intervention groups. Participants in both tailored intervention groups reported having colorectal cancer screening at significantly higher rates than participants in the generic print group. The increase in colorectal cancer screening in the tailored print and counseling call group was not significantly higher than that achieved by the tailored print alone. Decisional balance partially mediated treatment effects. Tailored behavioral interventions are effective methods for increasing screening adherence but telephone counseling did not add significantly to treatment effects.


Colorectal cancer screening Tailored interventions Intermediate risk siblings