Head and Neck Pathology

, Volume 5, Issue 4, pp 355–358

Metastatic Tumors to the Oral Cavity: A Clinical Study of 18 Cases

  • Bruno C. Jham
  • Andrew R. Salama
  • Shawn A. McClure
  • Robert A. Ord
Original Paper

DOI: 10.1007/s12105-011-0286-7

Cite this article as:
Jham, B.C., Salama, A.R., McClure, S.A. et al. Head and Neck Pathol (2011) 5: 355. doi:10.1007/s12105-011-0286-7


The aim of this study was to describe the clinical features of 18 cases of metastatic tumors to the oral cavity. The files of patients seen between 1992 and 2009 with oral (soft tissue and jawbones) metastatic lesions were reviewed. Clinical features, including gender, age, site of the primary tumor, site of metastatic tumor and treatment were evaluated. Patients were 11 males and 7 females, with mean age of 64.6 years. In males, most primary tumors originated in the lungs. In females, the lung and breast were the most common sites of the primary tumors. The mandible was the main site for the development of the metastatic lesions and the most common histologic type was adenocarcinoma. Treatment modalities included radiotherapy, chemotherapy and surgical resection. Metastatic lesions should be considered in the differential diagnosis of oral lesions, particularly when a previous history of cancer is present.


CancerMetastasisOral cavityClinical study

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Bruno C. Jham
    • 1
  • Andrew R. Salama
    • 2
  • Shawn A. McClure
    • 3
  • Robert A. Ord
    • 4
  1. 1.Department of Microbiology, Immunology, Parasitology and Pathology, Institute of Tropical Pathology and Public HealthFederal University of GoiásGoiâniaBrazil
  2. 2.Department of Dentistry and Oral & Maxillofacial Surgery, Boston Medical CenterBoston UniversityBostonUSA
  3. 3.Department of Oral and Maxillofacial SurgeryNova Southeastern University, College of Dental MedicineFort LauderdaleUSA
  4. 4.Department of Oral and Maxillofacial Surgery, University of Maryland Dental School, Marlene and Stuart Greenebaum Cancer CenterUniversity of Maryland Medical CenterBaltimoreUSA