, Volume 81, Issue 4, pp 325-327
Date: 16 Mar 2014

Kawasaki Disease: Unusual Clinical Manifestations

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Kawasaki disease (KD) is an acute febrile systemic vasculitis of unknown etiology and was first described in 1967 in Japan [1] and later in the English-language literature in 1974 by Tomisaku Kawasaki, who suggested the name mucocutaneous lymph node syndrome [2].

No definitive diagnostic laboratory test exists for KD [3, 4]. Diagnosis of KD is based on constellation of clinical features and supportive laboratory findings.

In this issue of IJP; Singh et al. discuss about missing KD during childhood and subsequent coronary artery disease (CAD) in adulthood [5]. They proposed that if incidence of KD is 4.54/100,000 in children below 15 y of age, about 17417 cases of KD may occur annually in India. In absence of authentic data it is difficult to confirm this figure but it can be assumed that majority of these patients are missed [6]. This raises an important hypothesis that identifying KD during childhood and treating them with appropriate intervention may reduce risk of CAD in adults. It is ...