, Volume 81, Issue 2, pp 203-204
Date: 24 Mar 2013

Invasive Meningococcal Disease: The Need for Immunization in Childhood

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To the Editor: We read with interest the paper by Dass Hazarika et al. describing analysis of 110 cases of invasive meningococcal disease (IMD) in North-Eastern India; purpura and rashes were noted in a quarter of cases (23.6 %) [1]. Wells et al. highlighted that only 11 % cases of non-blanching rash were associated with IMD; other conditions e.g., tonsillitis, Henoch Schönlein Purpura (HSP), were more frequent in clinical practice [2]. Meningococcal-C vaccine was introduced in the UK in 1999 and is likely to have further reduced the overall incidence of IMD. A recent Joint Committee on Vaccination and Immunisation (JCVI) report confirmed a 95 % fall in incidence of IMD caused by serogroup C Meningococcus in the UK [3].

A retrospective clinical audit (August’2010 to June’2012) was done to review all children admitted to pediatric ward with a non-blanching rash; our clinical management showed full compliance with the NICE guidelines [4]. Ninety-nine children were identified and computeri ...