, Volume 79, Issue 1, pp 130-131

Propranolol for Infantile Hemangiomas: Strawberry Matters?

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Hemangiomas are the most common benign tumor of childhood [13]. Occasionally hemangiomas can grow to a significant size causing deformity and be associated with sparodic bleeding and infection [24]. Such lesions need systemic treatment and whilst steroids have been favored in the past the serendipitous discovery of the therapeutic action of propranolol reported in 2008 heralded a global change in interventional strategies [1, 3, 4].

A mother noted a progressively enlarging left facial swelling when her daughter was 1 month old. The swelling was initially 1 cm in diameter but rapidly increased in size to 6 cm in 1 wk. There was no airway compromise or consumptive coagulopathy. Propranolol was started at 1.5 mg/kg/day at four divided doses. The dosage was halved due to hypotension. There appeared to be some initial reduction in the hemangioma size and the dosage was gradually increased. MRI at 3 months of age demonstrated a 4.4 × 4.5 × 5.8 cm lobulated enhancing hemangioma arising f