The Indian Journal of Pediatrics

, Volume 78, Issue 12, pp 1495–1497

Prevalence of Respiratory Syncytial Virus Infection among Hospitalized Children Presenting with Acute Lower Respiratory Tract Infections

  • Soham Gupta
  • Ranjani Shamsundar
  • Anita Shet
  • Rashmi Chawan
  • Hiresave Srinivasa
Original Article

DOI: 10.1007/s12098-011-0491-0

Cite this article as:
Gupta, S., Shamsundar, R., Shet, A. et al. Indian J Pediatr (2011) 78: 1495. doi:10.1007/s12098-011-0491-0

Abstract

Objective

To evaluate the prevalence of RSV among hospitalized young children presenting with ALRI in Bangalore, India.

Methods

Respiratory syncytial virus (RSV) antigen detection was performed by direct fluorescent antibody (DFA) staining on 77 nasopharyngeal wash samples collected from hospitalized children below 2 years of age with a diagnosis of acute lower respiratory tract infection (ALRI).

Results

Out of 77 samples tested for RSV with DFA, 17 (22.1%) were found RSV-positive with a mean age of 8.24 ± 7.21 months (M:F = 1.8:1). Three children had congenital cardiac disease and one child had a history of prematurity. One child had re-infection within one month of primary infection. RSV-infected children were more likely to have a diagnosis of bronchiolitis than RSV-negative children (p < 0.001).

Conclusions

RSV infection is a significant cause of morbidity among children presenting with ALRI in southern India. In resource-limited settings, DFA can be used as an important tool for rapid detection of RSV and can potentially eliminate prolonged hospitalization and unnecessary use of antibiotics.

Keywords

Respiratory syncytial virus (RSV) Acute lower respiratory tract infections (ALRTI) Direct fluorescent antibody staining (DFA) Epidemiology 

Copyright information

© Dr. K C Chaudhuri Foundation 2011

Authors and Affiliations

  • Soham Gupta
    • 1
  • Ranjani Shamsundar
    • 1
  • Anita Shet
    • 2
  • Rashmi Chawan
    • 1
  • Hiresave Srinivasa
    • 1
  1. 1.Department of MicrobiologySt. John’s Medical College and HospitalBangaloreIndia
  2. 2.Department of PediatricsSt. John’s Medical College and HospitalBangaloreIndia

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