The Indian Journal of Pediatrics

, Volume 77, Issue 11, pp 1288–1295

Intensive Care Management of Children with Acute Liver Failure


  • Vidyut Bhatia
    • Department of PediatricsAll India Institute of Medical Sciences
    • Department of PediatricsAll India Institute of Medical Sciences
Symposium on PICU Protocols of AIIMS

DOI: 10.1007/s12098-010-0167-1

Cite this article as:
Bhatia, V. & Lodha, R. Indian J Pediatr (2010) 77: 1288. doi:10.1007/s12098-010-0167-1


Acute liver failure is an uncommon condition associated with multi organ involvement, high morbidity and mortality. Etiology of acute liver failure varies with age and geographical location. Most cases of acute liver failure in India are due to infectious causes predominantly viral hepatitis. A significant group with indeterminate causation remains, despite careful investigation. The etiology of acute liver failure in infants is largely metabolic. The mainstay of management is supportive care in an intensive care unit. Monitoring of clinical and biochemical parameters is done frequently until the patient becomes stable. Mortality is predominantly due to raised intracranial pressure, infections and multi-organ failure. Liver transplant is an important life saving procedure for children with acute liver failure.


Acute liver failureViral hepatitisIntensive care management

Copyright information

© Dr. K C Chaudhuri Foundation 2010