The Indian Journal of Pediatrics

, Volume 77, Issue 3, pp 329–331

Migratory polyarthritis in familial hypercholesterolemia (type IIa hyperlipoproteinemia)

  • Partha Pratim Chakraborty
  • Sagnik Mukhopadhyay
  • Arun Achar
  • Mallika Pal
  • Prabodh Chandra Mondal
Clinical Brief

DOI: 10.1007/s12098-010-0021-5

Cite this article as:
Chakraborty, P.P., Mukhopadhyay, S., Achar, A. et al. Indian J Pediatr (2010) 77: 329. doi:10.1007/s12098-010-0021-5

Abstract

Metabolic disorders are often encountered in clinical practice. Some of these diseases are associated with dermatological and musculoskeletal manifestations. Familial hypercholesterolemia is a disorder of lipoprotein metabolism characterized by elevated cholesterol, low-density lipoprotein cholesterol, xanthomas and early onset atherosclerosis. Tendinitis and arthritis have been rarely reported in patients with familial hypercholesterolemia. Here is presented a case of a young girl with migratory polyarthritis, who was diagnosed as probable homozygote familial hypercholesterolemia with hypercholesterolemic arthritis. A proper knowledge of cutaneous manifestations helps to identify patients at risk, establish the underlying diagnosis, and start early and effective therapy.

Key words

Familial hypercholesterolaemia Migratory polyarthritis Foam cells Tuberous/ tendon xanthomas Type IIa Hyperlipoproteinemia 

Copyright information

© Dr. K C Chaudhuri Foundation 2010

Authors and Affiliations

  • Partha Pratim Chakraborty
    • 1
    • 5
  • Sagnik Mukhopadhyay
    • 1
  • Arun Achar
    • 2
  • Mallika Pal
    • 3
  • Prabodh Chandra Mondal
    • 4
  1. 1.Department of MedicineMidnapore Medical CollegePaschim MedinipurIndia
  2. 2.Department of Dermatology and VenereologyMidnapore Medical CollegePaschim MedinipurIndia
  3. 3.Department of PathologyMidnapore Medical CollegePaschim MedinipurIndia
  4. 4.Department of PediatricsMidnapore Medical CollegePaschim MedinipurIndia
  5. 5.Paschim MedinipurIndia