The Indian Journal of Pediatrics

, Volume 75, Issue 9, pp 947–949

Pediatric Scrub typhus in Indian Himalayas

  • Sanjay K. Mahajan
  • Jean-Marc Rolain
  • Naveen Sankhyan
  • Ram Krishan Kaushal
  • Didier Raoult
Clinical Brief

DOI: 10.1007/s12098-008-0198-z

Cite this article as:
Mahajan, S.K., Rolain, JM., Sankhyan, N. et al. Indian J Pediatr (2008) 75: 947. doi:10.1007/s12098-008-0198-z

Abstract

To retrospectively confirm the suspected rickettsial disease (Scrub typhus) using a gold standard diagnostic test i.e. microimmunofluorescence in pediatric patients with acute febrile illness of unknown etiology. Two serological tests, Weil-Felix and Microimmunofluorescence were used to confirm infection. All five children had fever, vomiting and generalized lymphadenopathy, but none had eschar or rash. One was cured with doxycycline, remaining four patients treated with azithromycin and one died despite treatment. Scrub typhus is a cause of fever of unknown origin in Himalayan region of India and azithromycin is an effective alternative to doxycycline in treating this disease.

Key words

Rickettsia Orientia tsutsugamushi Eschar Himachal Pradesh Azithromycin 

Copyright information

© Dr. K C Chaudhuri Foundation 2008

Authors and Affiliations

  • Sanjay K. Mahajan
    • 1
  • Jean-Marc Rolain
    • 2
  • Naveen Sankhyan
    • 1
  • Ram Krishan Kaushal
    • 1
  • Didier Raoult
    • 2
  1. 1.Department of PediatricsIG Medical CollegeShimlaIndia
  2. 2.URMITE UMR 6236, CNRS-IRDFaculte de Medecine et de PharmacieMarseilleFrance
  3. 3.Shimla-India

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