Original Article

The Indian Journal of Pediatrics

, Volume 74, Issue 10, pp 915-916

Efficacy of permethrin cream and oral ivermectin in treatment of scabies

  • Sarfrazul AbedinAffiliated withDepartment of Pediatrics, Rajiv Gandhi Cancer Institute
  • , Manish NarangAffiliated withDepartment of Pediatrics, Rajiv Gandhi Cancer InstituteDepartment of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital Email author 
  • , Vijay GandhiAffiliated withDepartment of Pediatrics, Rajiv Gandhi Cancer InstituteDepartment of Dermatology, University College of Medical Sciences and Guru Tegh Bahadur Hospital
  • , Shiva NarangAffiliated withDepartment of Pediatrics, Rajiv Gandhi Cancer InstituteDepartment of Medicine, University College of Medical Sciences and Guru Tegh Bahadur Hospital

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Abstract

Objective

To compare the efficacy of mass treatment of scabies with permethrin cream and oral ivermectin in a closed urban pediatric population.

Methods

A comparative trial of topical permethrin and oral ivermectin was conducted in a closed population of 84 children living in a urban hostel of Delhi.

Results

After mass treatment with 2 doses of oral ivermectin, one case was recorded in following 6 months, as compared to 22 cases in preceding 6 months when children were treated with a single application of 5% permethrin.

Conclusion

Mass treatment of scabies with ivermectin in an endemic population is more efficacious as compared to topical permethrin application in reducing the baseline prevalence, decreasing the chain of transmission and chances of reinfection.

Key words

Scabies Ivermectin Permethrin