The Indian Journal of Pediatrics

, Volume 74, Issue 10, pp 915–916

Efficacy of permethrin cream and oral ivermectin in treatment of scabies

  • Sarfrazul Abedin
  • Manish Narang
  • Vijay Gandhi
  • Shiva Narang
Original Article

DOI: 10.1007/s12098-007-0168-x

Cite this article as:
Abedin, S., Narang, M., Gandhi, V. et al. Indian J Pediatr (2007) 74: 915. doi:10.1007/s12098-007-0168-x

Abstract

Objective

To compare the efficacy of mass treatment of scabies with permethrin cream and oral ivermectin in a closed urban pediatric population.

Methods

A comparative trial of topical permethrin and oral ivermectin was conducted in a closed population of 84 children living in a urban hostel of Delhi.

Results

After mass treatment with 2 doses of oral ivermectin, one case was recorded in following 6 months, as compared to 22 cases in preceding 6 months when children were treated with a single application of 5% permethrin.

Conclusion

Mass treatment of scabies with ivermectin in an endemic population is more efficacious as compared to topical permethrin application in reducing the baseline prevalence, decreasing the chain of transmission and chances of reinfection.

Key words

ScabiesIvermectinPermethrin

Copyright information

© Dr. K C Chaudhuri Foundation 2007

Authors and Affiliations

  • Sarfrazul Abedin
    • 1
  • Manish Narang
    • 1
    • 2
  • Vijay Gandhi
    • 1
    • 3
  • Shiva Narang
    • 1
    • 4
  1. 1.Department of PediatricsRajiv Gandhi Cancer InstituteDelhiIndia
  2. 2.Department of PediatricsUniversity College of Medical Sciences and Guru Tegh Bahadur HospitalDelhiIndia
  3. 3.Department of DermatologyUniversity College of Medical Sciences and Guru Tegh Bahadur HospitalDelhiIndia
  4. 4.Department of MedicineUniversity College of Medical Sciences and Guru Tegh Bahadur HospitalDelhiIndia
  5. 5.Dilshad Garden, DelhiIndia