The Indian Journal of Pediatrics

, Volume 74, Issue 4, pp 412–415

Osteopetrosis with Arnold Chiari malformation type I and brain stem compression

Authors

  • M. L. Kulkarni
    • Department of Pediatrics J.J.M. Medical College
  • S. N. Marakkanavar
    • Department of Pediatrics J.J.M. Medical College
  • S. Sushanth
    • Department of Pediatrics J.J.M. Medical College
  • N. Pradeep
    • Department of Pediatrics J.J.M. Medical College
  • C. Ashok
    • Department of Pediatrics J.J.M. Medical College
  • M. D. Balaji
    • Department of Pediatrics J.J.M. Medical College
  • K. P. Sajith
    • Department of Pediatrics J.J.M. Medical College
  • G. Srinivas
    • Department of Pediatrics J.J.M. Medical College
Clinical Brief

DOI: 10.1007/s12098-007-0070-6

Cite this article as:
Kulkarni, M.L., Marakkanavar, S.N., Sushanth, S. et al. Indian J Pediatr (2007) 74: 412. doi:10.1007/s12098-007-0070-6

Abstract

Osteopetrosis is a collective term for a range of sclerosing bone diseases resulting from an absence or defective function of osteoclasts. The clinical expression is variable and includes skeletal, hematological and neurological manifestations. The common neurological manifestation includes cranial neuropathies involving optic, cochlear, facial and trigeminal nerves. Spastic quadriplegia occurring as a result of brain stem compression in osteopetrosis is uncommon. The association of Type 1 Arnold Chiari malformation with osteopetrosis resulting in brain stem compression syndrome is an extremely rare entity.

Key words

OsteopetrosisArnold chiari malformationBrain stem compressionSyringiomyelia

Copyright information

© Dr. K C Chaudhuri Foundation 2007