The Indian Journal of Pediatrics

, Volume 74, Issue 1, pp 73–77

Bronchopulmonary dysplasia: An update

Symposium: Neonatology II Evidence and Experience in Neonatal Medicine

DOI: 10.1007/s12098-007-0032-z

Cite this article as:
Bhandari, A. & Bhandari, V. Indian J Pediatr (2007) 74: 73. doi:10.1007/s12098-007-0032-z


Bronchopulmonary dysplasia (BPD) is a chronic lung disease associated with premature birth and characterized by early lung injury. Over the past 4 decades, there have been significant changes in its definition, pathology and radiological findings as well as management of BPD. Management of the acute phase and later stages of this lung disease continue to evolve. Use of non-invasive ventilatory techniques, recombinant human SOD and CC10 and inhaled NO are some novel approaches that are being studied. Adequate nutrition is vital to optimize lung growth and repair. The widely accepted practice of prophylaxis against viral infections has markedly decreased the rates of rehospitalization. Infants with BPD, however, continue to have significant pulmonary and neurodevelopmental sequelae. Unraveling the genetic contribution to BPD will potentially pave the way to improved preventive and therapeutic approaches.

Key words

BPDPrematurityChronic lung disease

Copyright information

© Dr. K C Chaudhuri Foundation 2007

Authors and Affiliations

  1. 1.Division of Perinatal Medicine, Department of Pediatrics LCI 401BYale University School of MedicineNew HavenUSA
  2. 2.Division of Pediatric Pulmonology, Connecticut Children’s Medical CenterNew HavenUSA