Clinical Guides in Oncology

Clinical and Translational Oncology

, Volume 14, Issue 7, pp 499-504

Treatment of cancer pain: Spanish Society of Medical Oncology (SEOM) recommendations for clinical practice

  • Juan A. VirizuelaAffiliated withMedical Oncology Department, Hospital Virgen Macarena Email author 
  • , Yolanda EscobarAffiliated withMedical Oncology Department, Hospital General Universitario Gregorio Marañón
  • , Javier CassinelloAffiliated withMedical Oncology Department, Hospital Universitario de Guadalajara
  • , Pablo BorregaAffiliated withMedical Oncology Department, Hospital San Pedro de Alcántara

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Cancer pain should be controlled in most patients, however this is not always achieved. These guidelines describe the classification, evaluation and treatment of chronic cancer pain in accordance with the WHO treatment strategy of pain stages: mild, moderate and severe. For treatment during the third stage, we cover titration and rotation of opioids, as well as their side effects and prevention. Also described is neuropathic pain and refractory pain, coadjuvant treatments and non pharmacological analgesic treatments. Finally, treatment of breakthrough pain is defined.


Chronic cancer pain Evaluation Opioids Breakthrough pain Neuropathic pain Coanalgesics