Clinical and Translational Oncology

, Volume 12, Issue 5, pp 356–366

TTD consensus document on the diagnosis and management of hereditary colorectal cancer

  • Pedro Pérez Segura
  • Carmen Guillén Alonso
  • Teresa Ramón y Cajal
  • Raquel Serrano Blanch
  • Enrique Aranda
Special Article

DOI: 10.1007/s12094-010-0517-5

Cite this article as:
Pérez Segura, P., Guillén Alonso, C., Ramón y Cajal, T. et al. Clin Transl Oncol (2010) 12: 356. doi:10.1007/s12094-010-0517-5
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Abstract

Colorectal cancer is the first cause of cancer in occidental countries if we consider both male and females tumours. In Spain, 26,000 new cases are diagnosed every year. The possibilities of cure are higher if the tumour is diagnosed early. One of the most important risk factors for colorectal cancer is inheritance. Some hereditary syndromes, such as familial adenomatous polyposis (FAP), increase the risk by almost 100% and at a young age. Other more prevalent syndromes, such Lynch syndrome, increase the risk 10–12 times more than in the general population. This article aims at summarising the most important aspects in hereditary colorectal cancer and to be a useful tool to oncologists who work with these patients and their families.

Keywords

Colorectal cancerHereditaryConsensusManagement

Copyright information

© Feseo 2010

Authors and Affiliations

  • Pedro Pérez Segura
    • 1
  • Carmen Guillén Alonso
    • 2
  • Teresa Ramón y Cajal
    • 3
  • Raquel Serrano Blanch
    • 4
  • Enrique Aranda
    • 4
  1. 1.Medical Oncology DepartmentHospital Clínico San CarlosMadridSpain
  2. 2.Medical Oncology DepartmentHospital Ramón and CajalMadridSpain
  3. 3.Medical Oncology DepartmentHospital Sant PauBarcelonaSpain
  4. 4.Medical Oncology DepartmentHospital Reina SofíaCórdobaSpain