Special Article

Clinical and Translational Oncology

, Volume 9, Issue 5, pp 308-316

First online:

Treatment guidelines in ovarian cancer

  • A. Poveda VelascoAffiliated withServicio de Oncología Médica, Fundación Instituto Valenciano de Oncología Email author 
  • , A. Casado HerráezAffiliated withServicio de Oncología Médica, Hospital Universitario San Carlos
  • , A. Cervantes RuipérezAffiliated withServicio de Hematología y Oncología Médica, Hospital Clínico Universitario de Valencia
  • , D. Gallardo RincónAffiliated withInstituto Nacional de Cancerología
  • , E. García GarcíaAffiliated withServicio de Oncología Médica, Fundación Instituto Valenciano de Oncología
  • , A. González MartínAffiliated withServicio de Oncología Médica, Hospital Ramón y Cajal
  • , G. López GarcíaAffiliated withClínica Universitaria de Navarra
  • , C. Mendiola FernándezAffiliated withServicio de Oncología Médica, Hospital Universitario 12 de Octubre
  • , B. Ojeda GonzálezAffiliated withServicio de Oncología Médica, Hospital de la Santa Creu i Sant Pau

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Abstract

National and international specialists have met with the aim of writing down the guidelines for the treatment of epithelial ovarian cancer (in the Spanish Castilian language). These guidelines are based on the International Consensus that was published in English in the Annals of Oncology in 2005. This condition is the leading cause of death from gynaecological cancer in western countries. Its low rate of survival, barely 30% at 5 years, is above all due to late diagnosis and inappropriate surgery, so emphasis is put on these aspects. After describing the methodology for early detection and a scheme of surgical diagnostic procedures in view of the staging of an ovarian mass, the following therapeutic strategies will be recommended: cytoreductive surgery together with platinum chemotherapy under normal conditions, and also in the case of relapse. Likewise, very recent models of treatment focused on molecular targets are presented, and a broad section on methodology of clinical assays. As for this, co-operation among groups is crucial in order to make the conclusions of these studies valid for the development of new therapies.

Key words

Ovarian cancer Treatment guidelines Adjuvant chemotherapy Surgical procedures