, Volume 5, Issue 1, p 1
Date: 22 Feb 2012

An Introduction to this Special Issue: Neuroimaging in the Chemical Senses

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This special issue of Chemosensory Perception is devoted to neuroimaging investigations of the chemical senses. While there were early efforts by Lord Adrian and R.W. Moncrieff to image chemosensory responses in the brain, and later investigations by others using EEG, the modern era of chemosensory neuroimaging really began in 1992 with the publication of “Functional localization and lateralization of human olfactory cortex” by Zatorre, Jones-Gotman, Evans, and Meyer in the journal Nature. In that study, long-handled cotton swamps saturated with odorant were waved in front of the nose and, to use the vernacular of the day, the piriform cortex “lit up.” Since that landmark study, some 20 years ago, the field has expanded dramatically. PET has largely been replaced with functional magnetic resonance imaging and advanced electro- and magneto-encephalographic techniques. Cotton wands have been replaced with fMRI compatible olfactometers equipped to measure sniffs, temperature, and humidity