Hepatology International

, Volume 4, Issue 3, pp 653–658

Adult Langerhans cell histiocytosis and sclerosing cholangitis: a case report and review of the literature

  • Ibrahim Hatemi
  • Birol Baysal
  • Hakan Senturk
  • Kemal Behzatoglu
  • Erol Rustu Bozkurt
  • Gulsen Ozbay
Case Report

DOI: 10.1007/s12072-010-9205-3

Cite this article as:
Hatemi, I., Baysal, B., Senturk, H. et al. Hepatol Int (2010) 4: 653. doi:10.1007/s12072-010-9205-3

Abstract

Background/aims

Sclerosing cholangitis is a rare complication of Langerhans cell histiocytosis in children which can result in liver failure. This combination is even rarer in adults.

Case report

We report a 65-year-old female who developed sclerosing cholangitis 4 years after the diagnosis of Langerhans cell histiocytosis.

Conclusion

Sclerosing cholangitis caused by Langerhans cell histiocytosis is a rare condition in the adult population, but it has a high mortality. There is no definitive therapy other than liver transplantation. The long-term efficacy of liver transplantation remains unknown.

Keywords

Langerhans cell histiocytosisSclerosing cholangitis

Copyright information

© Asian Pacific Association for the Study of the Liver 2010

Authors and Affiliations

  • Ibrahim Hatemi
    • 1
  • Birol Baysal
    • 1
  • Hakan Senturk
    • 1
  • Kemal Behzatoglu
    • 2
  • Erol Rustu Bozkurt
    • 2
  • Gulsen Ozbay
    • 1
  1. 1.Division of Gastroenterology, Department of Internal MedicineIstanbul University Cerrahpasa Medical FacultyAksaray, IstanbulTurkey
  2. 2.Department of Pathology, Istanbul Education and Research HospitalAbdurrahman Nafiz Gurman Caddesi Kocamustafapasa FatihIstanbulTurkey