Kosambi and the genetic mapping function
- K. K. Vinod
- … show all 1 hide
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
One of the activities that geneticists pursue is the generation of genetic maps of organisms that chart the locations of the different genes on the chromosomes. Damodar Dharmanada Kosambi was not a geneticist by training and profession, but amathematician. Yet, in 1944, Kosambi wrote a classic paper about mapping function in genetics in the journal Annals of Eugenics. His lone paper in genetics was tilted ‘The estimation of map distance from recombination values’. The mapping function that Kosambi derived is still widely used by geneticists the world over for the mapping of genomes.
- D D Kosambi, The estimation of map distance from recombination values, Annals of Eugenics, Vol.12, pp.172–175, 1944. CrossRef
- W Bateson, E R Saun-ders and R C Punnet, Experimental studies in the physiology of heredity, Reports to the Evolution Committee of the Royal Society, Vol.2, pp.80–99, 1905.
- T H Morgan and C B Bridges, Sex linked inheritance in Drosophila, Carnegie Institution of Washington. p.88, 1916.
- J B S Haldane, The combination of linkage values, and the calculation of distance between linked factors, Journal of Genetics, Vol.8, pp.299–309, 1919. CrossRef
- B H Liu, Statistical Genomics: Linkage, Mapping, and QTL Analysis, CRC Press, p.611, 1997.
- M Huehn, Random variability of map distances based on Kosambi’s and Haldane’s mapping functions, J. Appl. Genet., Vol.51, pp.27–31, 2010. CrossRef
- Kosambi and the genetic mapping function
Volume 16, Issue 6 , pp 540-550
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- genetic interference
- Industry Sectors
- K. K. Vinod (1)
- Author Affiliations
- 1. Rice Breeding and Genetics Research Centre Aduthurai, IARI, 612 101, Tanjavur District, TN, India