, Volume 15, Issue 2, pp 131–153

Systems biology

General / Article

DOI: 10.1007/s12045-010-0015-7

Cite this article as:
Raman, K. & Chandra, N. Reson (2010) 15: 131. doi:10.1007/s12045-010-0015-7


Systems biology seeks to study biological systems as a whole, contrary to the reductionist approach that has dominated biology. Such a view of biological systems emanating from strong foundations of molecular level understanding of the individual components in terms of their form, function and interactions is promising to transform the level at which we understand biology. Systems are defined and abstracted at different levels, which are simulated and analysed using different types of mathematical and computational techniques. Insights obtained from systems level studies readily lend to their use in several applications in biotechnology and drug discovery, making it even more important to study systems as a whole.


Pathway modellingsystems modellingbiological networkscomplex systems

Copyright information

© Indian Academy of Sciences 2010

Authors and Affiliations

  1. 1.Department of BiochemistryUniversity of ZurichZurichSwitzerland
  2. 2.Bioinformatics Centre Raman buildingIndian Institute of ScienceBangaloreIndia