, Volume 123, Issue 4, pp 485-489
Date: 30 Jul 2011

Recyclable nickel catalysed Suzuki–Miyaura reaction in the presence of polyethyleneimine under phosphine-free conditions in ethylene glycol#

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Abstract

In this report, Suzuki–Miyaura coupling reaction was performed in the presence of polyethyleneimine (PEI) as ligand, NiCl2·6H2O and K2CO3 in ethylene glycol at 80–100°C under phosphine-free conditions. By this method, structurally different aryl bromides and iodides were reacted with phenylboronic acid and potassium phenyltrifluoroborate. Under these simple reaction conditions a different biaryl derivatives have been prepared in high to excellent yields. Recycling experiments showed that catalyst can be used as recyclable catalyst in the Suzuki–Miyaura cross-coupling reactions.

Graphical Abstract

Suzuki–Miyaura reaction of structurally different aryl iodides and bromides with phenylboronic acid and potassium phenyltrifluoroborate in the presence of polyethyleneimine (PEI), NiCl2·6H2O andK2CO3 in ethylene glycol at 80–100°C under phosphine free conditions was performed.

This paper is dedicated to Professor Habib Firouzabadi on the occasion of his 68th birthday