Journal of Biosciences

, 34:543

The other side of phenotypic plasticity: a developmental system that generates an invariant phenotype despite environmental variation

Article

DOI: 10.1007/s12038-009-0073-8

Cite this article as:
Braendle, C. & Félix, M. J Biosci (2009) 34: 543. doi:10.1007/s12038-009-0073-8

Abstract

Understanding how the environment impacts development is of central interest in developmental and evolutionary biology. On the one hand, we would like to understand how the environment induces phenotypic changes (the study of phenotypic plasticity). On the other hand, we may ask how a development system maintains a stable and precise phenotypic output despite the presence of environmental variation. We study such developmental robustness to environmental variation using vulval cell fate patterning in the nematode Caenorhabditis elegans as a study system. Here we review both mechanistic and evolutionary aspects of these studies, focusing on recently obtained experimental results. First, we present evidence indicating that vulval formation is under stabilizing selection. Second, we discusss quantitative data on the precision and variability in the output of the vulval developmental system in different environments and different genetic backgrounds. Third, we illustrate how environmental and genetic variation modulate the cellular and molecular processes underlying the formation of the vulva. Fourth, we discuss the evolutionary significance of environmental sensitivity of this developmental system.

Keywords

Caenorhabditis elegansdevelopmental plasticityenvironmentrobustnessvulval cell fate patterning

Copyright information

© Indian Academy of Sciences 2009

Authors and Affiliations

  1. 1.Institut Jacques MonodParis cedex 05France
  2. 2.Institute of Developmental Biology and CancerUniversity of Nice Sophia-AntipolisNice cedex 2France