Journal of Biosciences

, 33:571

Human cysticercosis and Indian scenario: a review

  • Kashi Nath Prasad
  • Amit Prasad
  • Avantika Verma
  • Aloukick Kumar Singh
Article

DOI: 10.1007/s12038-008-0075-y

Cite this article as:
Prasad, K.N., Prasad, A., Verma, A. et al. J Biosci (2008) 33: 571. doi:10.1007/s12038-008-0075-y

Abstract

Cysticercosis, caused by Taenia solium larva is a major public health problem, especially in the developing world and neurocysticercosis (NCC) is considered to be the most common parasitic infestation of the central nervous system. NCC is identified as the single most common cause of community acquired active epilepsy; 26.3% to 53.8% active epilepsy cases in the developing world including India and Latin America are due to NCC. It is also becoming more common in the developed world because of increased migration of people with the disease or Taenia solium carriers and frequent travel to the endemic countries. It is estimated that three quarters of the estimated 50 million people with active epilepsy live in the poor countries of the world. Recent Indian studies using neuroimaging techniques suggest that the disease burden in India surpasses many other developing countries. Hence it is important to know the epidemiology, pathogenesis and diagnostic criteria so as to assess the disease burden and adopt interventional strategies for its control. Literature search was done for this review with special emphasis on Indian studies to create awareness about the disease in India, since cysticercosis is preventable and potentially eradicable.

Keywords

Active epilepsycysticercosisneurocysticercosisseizuretaeniasisTaenia solium

Abbreviations used

AHDs

antihelminthic drugs

CNS

central nervous system

CFT

complement fixation tests

CSF

cerebrospinal fluid

EITB

enzyme electroimmune transfer blot

ELISA

enzyme linked immunosorbent assay

IHA

indirect haemagglutination tests

JE

Japanese encephalitis

LTT

lymphocyte transformation test

MRI

magnetic resonance imaging

NCC

neurocysticercosis

Copyright information

© Indian Academy of Sciences 2008

Authors and Affiliations

  • Kashi Nath Prasad
    • 1
  • Amit Prasad
    • 1
  • Avantika Verma
    • 1
  • Aloukick Kumar Singh
    • 1
  1. 1.Department of MicrobiologySanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia