Review

Molecular Biotechnology

, Volume 42, Issue 1, pp 1-13

Data Deposition and Annotation at the Worldwide Protein Data Bank

  • Shuchismita DuttaAffiliated withResearch Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
  • , Kyle BurkhardtAffiliated withResearch Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), Department of Chemistry and Chemical Biology, Rutgers, The State University of New JerseyOffice of Research and Project Administration, Princeton University
  • , Jasmine YoungAffiliated withResearch Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
  • , Ganesh J. SwaminathanAffiliated withThe Macromolecular Structure Database at the European Bioinformatics Institute PDB-e, EMBL Outstation-Hinxton
  • , Takanori MatsuuraAffiliated withProtein Data Bank Japan (PDBj), Institute for Protein Research, Osaka University
  • , Kim HenrickAffiliated withThe Macromolecular Structure Database at the European Bioinformatics Institute PDB-e, EMBL Outstation-Hinxton
  • , Haruki NakamuraAffiliated withProtein Data Bank Japan (PDBj), Institute for Protein Research, Osaka University
  • , Helen M. BermanAffiliated withResearch Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey Email author 

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Abstract

The Protein Data Bank (PDB) is the repository for three-dimensional structures of biological macromolecules, determined by experimental methods. The data in the archive is free and easily available via the Internet from any of the worldwide centers managing this global archive. These data are used by scientists, researchers, bioinformatics specialists, educators, students, and general audiences to understand biological phenomenon at a molecular level. Analysis of this structural data also inspires and facilitates new discoveries in science. This chapter describes the tools and methods currently used for deposition, processing, and release of data in the PDB. References to future enhancements are also included.

Keywords

Protein Data Bank (PDB) wwPDB Deposition Annotation Validation