Molecular Biotechnology

, Volume 39, Issue 1, pp 1–8

The Evaluation of Protein Structure Prediction Results

Authors

  • Domenico Cozzetto
    • Department of Biochemical Sciences “Rossi Fanelli”University of Rome “La Sapienza”
  • Alejandro Giorgetti
    • Department of Biochemical Sciences “Rossi Fanelli”University of Rome “La Sapienza”
  • Domenico Raimondo
    • Department of Biochemical Sciences “Rossi Fanelli”University of Rome “La Sapienza”
    • Department of Biochemical Sciences “Rossi Fanelli”University of Rome “La Sapienza”
    • Istituto Pasteur-Fondazione Cenci BolognettiUniversity of Rome “La Sapienza”
Review

DOI: 10.1007/s12033-007-9023-6

Cite this article as:
Cozzetto, D., Giorgetti, A., Raimondo, D. et al. Mol Biotechnol (2008) 39: 1. doi:10.1007/s12033-007-9023-6

Abstract

Methods for protein structure prediction are flourishing and becoming widely available to both experimentalists and computational biologists. However, how good are they? What is their range of applicability and how can we know which method is better suited for the task at hand? These are the questions that this review tries to address, by describing the worldwide Critical Assessment of techniques for protein Structure Prediction (CASP) initiative and focusing on the specific problems of assessing the quality of a protein 3D model.

Keywords

Protein structure predictionAccuracy of protein structure modelsCASPStructure prediction serversMetapredictors

Copyright information

© Humana Press Inc. 2007