Medical Oncology

, Volume 28, Supplement 1, pp 644–646

Activity of trabectidin in desmoplastic small round cell tumor

  • Ana López-González
  • Blanca Cantos
  • Eva Tejerina
  • Mariano Provencio
Article

DOI: 10.1007/s12032-010-9687-9

Cite this article as:
López-González, A., Cantos, B., Tejerina, E. et al. Med Oncol (2011) 28: 644. doi:10.1007/s12032-010-9687-9

Abstract

Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive cancer that typically arises in teenage boys. As a result of its low prevalence, there have been few studies of its treatment and impact on survival. Here, we report the case of a patient who was refractory to multiple drugs but remains stable with trabectedin. To our knowledge, this is the first published report that supports antitumoral activity of trabectedin in DSRCT.

Keywords

Desmoplastic small round cell tumorEWT/WT1 fusion transcriptTrabectidin

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Ana López-González
    • 1
  • Blanca Cantos
    • 1
  • Eva Tejerina
    • 2
  • Mariano Provencio
    • 1
  1. 1.Medical OncologyHospital Universitario Puerta de HierroMadridSpain
  2. 2.Pathology AnatomyHospital Universitario Puerta de HierroMadridSpain