Journal of Gastrointestinal Cancer

, Volume 44, Issue 1, pp 115–117

Pregnancy with Metastatic Gastrointestinal Stromal Tumor (GIST) on Imatinib Chemotherapy: an Oncologist’s Nightmare and Obstetrician’s Dilemma

Authors

  • Neerja Goel
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
  • Balkesh Rathi
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
  • Sruthi Bhaskaran
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
  • Shalini Rajaram
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
  • Sumita Mehta
    • Department of Obstetrics and GynecologyUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
  • Nitin Agarwal
    • Department of SurgeryUniversity College of Medical Sciences and Guru Teg Bahadur Hospital
Brief Communication

DOI: 10.1007/s12029-012-9464-4

Cite this article as:
Goel, N., Malik, R., Rathi, B. et al. J Gastrointest Canc (2013) 44: 115. doi:10.1007/s12029-012-9464-4

Abstract

Introduction

Gastrointestinal stromal tumors (GISTs) are among the few cancers amenable to successful treatment by targeted molecular therapy with KIT receptor inhibitors like imatinib mesylate. Increasing incidence of this tumor and its successful treatment has given rise to issues of fertility and child bearing in patients affected at young age. Although contraception advice and termination of early pregnancy have been the standard practice in patients on such therapy, an occasional patient who desires pregnancy can leave both obstetrician and oncologist perplexed.

Clinical Presentation

We report our experience in a rare patient of metastatic GIST who had a successful normal pregnancy while on imatinib therapy. We further attempt to evaluate similar evidence in literature.

Keywords

Metastatic gastrointestinal stromal tumorPregnancyImatinibCancer chemotherapy

Copyright information

© Springer Science+Business Media New York 2012