Journal of Gastrointestinal Cancer

, Volume 43, Issue 4, pp 521–525

Diagnostic and Therapeutic Challenges in Hepatic Epithelioid Hemangioendothelioma

Authors

    • Department of MedicineVanderbilt University Medical Center
  • D. Lee Gorden
    • Department of Surgery, Division of Hepatobiliary Surgery and Liver TransplantationVanderbilt University Medical Center
  • Jacob F. Busler
    • Department of Pathology, Microbiology, and ImmunologyVanderbilt University Medical Center
  • Alice C. Coogan
    • Department of Pathology, Microbiology, and ImmunologyVanderbilt University Medical Center
  • Beau S. Kelly
    • Department of Surgery, Division of Hepatobiliary Surgery and Liver TransplantationVanderbilt University Medical Center
Review Article

DOI: 10.1007/s12029-012-9389-y

Cite this article as:
Mistry, A.M., Gorden, D.L., Busler, J.F. et al. J Gastrointest Canc (2012) 43: 521. doi:10.1007/s12029-012-9389-y

Abstract

Background

Epithelioid hemangioendothelioma is a very rare, low-grade vascular tumor known to arise in soft tissues and visceral organs. Clinical diagnosis of hepatic epithelioid hemangioendothelioma remains a challenge, and although it is frequently managed with a liver transplant due to its multifocal nature, recurrence is a common complication.

Methods

We review recent advances in the diagnosis of hepatic epithelioid hemangioendothelioma, including major genetic breakthroughs, and discuss efforts to reduce post-liver transplant recurrence of hepatic epithelioid hemangioendothelioma.

Keywords

Hepatic epithelioid hemangioendothelioma Epithelioid hemangioendothelioma HEHE EHE

Copyright information

© Springer Science+Business Media, LLC 2012