Neurocritical Care

, Volume 12, Issue 2, pp 204–210

Electroconvulsive Therapy for Refractory Status Epilepticus: A Case Series

  • Hooman Kamel
  • Susannah Brock Cornes
  • Manu Hegde
  • Stephen E. Hall
  • S. Andrew Josephson
Original Article

DOI: 10.1007/s12028-009-9288-7

Cite this article as:
Kamel, H., Cornes, S.B., Hegde, M. et al. Neurocrit Care (2010) 12: 204. doi:10.1007/s12028-009-9288-7

Abstract

Background

Status epilepticus refractory to conventional anti-epileptic drugs typically has a poor prognosis, but patients may recover well if seizures can be stopped. Case reports suggest that electroconvulsive therapy (ECT) may stop seizures in patients with refractory status epilepticus, and we sought to examine its effectiveness in a series of patients.

Methods

Three consecutive patients with refractory status epilepticus at our institution were treated with ECT after other therapies had failed.

Results

ECT stopped seizures in 2 of 3 patients. One patient had complete neurological recovery; the other was left with mild cognitive impairment and epilepsy, but returned to independent living.

Conclusion

ECT may be an effective therapy for refractory status epilepticus and warrants further study for this indication.

Keywords

Status epilepticusElectroconvulsive therapyAnticonvulsants

Copyright information

© Humana Press Inc. 2009

Authors and Affiliations

  • Hooman Kamel
    • 1
  • Susannah Brock Cornes
    • 1
  • Manu Hegde
    • 1
  • Stephen E. Hall
    • 2
  • S. Andrew Josephson
    • 1
  1. 1.Department of NeurologyUniversity of CaliforniaSan FranciscoUSA
  2. 2.Department of PsychiatryUniversity of CaliforniaSan FranciscoUSA