Endocrine Pathology

, Volume 24, Issue 2, pp 106–109

Pituitary Adenoma with Mucin Cells in a Man with an Unusual Presentation of Carney Complex

  • Gabrielle A. Yeaney
  • Jillene M. Brathwaite
  • Matthew L. Dashnaw
  • G. Edward Vates
  • Laura M. Calvi
Article

DOI: 10.1007/s12022-013-9247-x

Cite this article as:
Yeaney, G.A., Brathwaite, J.M., Dashnaw, M.L. et al. Endocr Pathol (2013) 24: 106. doi:10.1007/s12022-013-9247-x

Abstract

We describe a 44-year-old man with infertility, acromegaly, and hypergonadotropic hypogonadism. Clinical examination of the patient revealed hyperpigmented macules on the lips, buccal mucosa, and face which were histologically confirmed as cutaneous myxomas and blue nevi. Ultrasound revealed testicular calcifications and multiple hypoechoic thyroid nodules. MR imaging showed a pituitary microadenoma and resection revealed it to be a growth hormone and prolactin-secreting adenoma with the unusual finding of admixed individual mucin-producing cells. We discuss mucin cells in pituitary adenoma, an unreported pathologic finding in a patient with Carney complex.

Keywords

Carney complex Mucin Pituitary adenoma Acromegaly Prolactin 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Gabrielle A. Yeaney
    • 1
  • Jillene M. Brathwaite
    • 2
  • Matthew L. Dashnaw
    • 3
  • G. Edward Vates
    • 3
  • Laura M. Calvi
    • 2
  1. 1.Departments of Pathology and Laboratory Medicine and OphthalmologyUniversity of Rochester School of Medicine and DentistryRochesterUSA
  2. 2.Division of Endocrinology and Metabolism, Department of MedicineUniversity of Rochester School of Medicine and DentistryRochesterUSA
  3. 3.Department of NeurosurgeryUniversity of Rochester School of Medicine and DentistryRochesterUSA