Endocrine Pathology

, Volume 22, Issue 4, pp 184–189

Follicular-Patterned Tumors of the Thyroid: The Battle of Benign vs. Malignant vs. So-called Uncertain


DOI: 10.1007/s12022-011-9183-6

Cite this article as:
LiVolsi, V.A. & Baloch, Z.W. Endocr Pathol (2011) 22: 184. doi:10.1007/s12022-011-9183-6


This article will review the controversial area of follicular-patterned thyroid tumors. The literature is discussed with emphasis on pathologic diagnosis and the criteria for malignancy. In addition, the current state of knowledge regarding molecular markers and their utility in diagnosing benign from malignant nodules is described. Finally, the apparent lack of consistency with regard to results of certain immunohistochemical markers is included.


Thyroid cancer Follicular tumors Follicular variant of papillary carcinoma 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory Medicine, Division of Anatomic PathologyUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of Pathology and Laboratory MedicinePerelman School of Medicine, University of PennsylvaniaPhiladelphiaUSA

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